Antibiotic resistance determinants in Acinetobacter spp

"Antibiotic resistance determinants in Acinetobacter spp and clinical outcomes in patients from a major military treatment facility"
Am J Infect Control. 2010 Feb
Perez F, Hujer AM, Hulten EA, Fishbain J, Hujer KM, Aron D, Thweatt K, Donskey CJ, Bonomo RA.

We explored the association of antibiotic-resistant phenotypes and genotypes in Acinetobacter spp with clinical outcomes and characteristics in 75 patients from a major military treatment facility. Amikacin resistance was associated with nosocomial acquisition of A baumannii, and carbapenem resistance and bla(OXA-23) were associated with the need for mechanical ventilation. The presence of bla(OXA-23) also correlated with longer hospital and ICU stay. Associations between bla(OXA-23) and complexity, duration, and changes made to antibiotic regimens also existed. Copyright 2010. Published by Mosby, Inc.

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